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non-diabetic primary human coronary artery vsmcs  (Thermo Fisher)


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    Structured Review

    Thermo Fisher non-diabetic primary human coronary artery vsmcs
    <t>Diabetic</t> patient <t>vSMCs</t> exhibit DNA damage and low SIRT1 expression. ( A ) Double stranded DNA breaks were assessed via the comet assay in control ( n = 6) and diabetic (DM) ( n = 6) vSMCs. Tail moment and tail DNA percentage were calculated via CASPLab. Scale bar = 20μm. ( B ) Telomere length of control ( n = 6) and DM ( n = 6) vSMCs was quantified via qPCR and normalised to Col3a1 and Col6a1. ( C ) p21 ( n = 6) ( D ) p53, ( n = 6) ( E ) ATM ( n = 6) and ( F ) SIRT1 ( n = 6) mRNA expression from DM vSMCs was compared to controls via qPCR. ( G ) SIRT1 protein expression within DM and control vSMCs was assessed by western blot analysis and normalized to α-tubulin ( n = 6). A Mann–Whitney U test was performed. * P < 0.05, ** P < 0.01, *** P < 0.001.
    Non Diabetic Primary Human Coronary Artery Vsmcs, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/non-diabetic+primary+human+coronary+artery+vsmcs/pmc07898956-36-0-9
    Average 90 stars, based on 1 article reviews
    non-diabetic primary human coronary artery vsmcs - by Bioz Stars, 2026-10
    90/100 stars

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    1) Product Images from "Loss of SIRT1 in diabetes accelerates DNA damage-induced vascular calcification"

    Article Title: Loss of SIRT1 in diabetes accelerates DNA damage-induced vascular calcification

    Journal: Cardiovascular Research

    doi: 10.1093/cvr/cvaa134

    Diabetic patient vSMCs exhibit DNA damage and low SIRT1 expression. ( A ) Double stranded DNA breaks were assessed via the comet assay in control ( n = 6) and diabetic (DM) ( n = 6) vSMCs. Tail moment and tail DNA percentage were calculated via CASPLab. Scale bar = 20μm. ( B ) Telomere length of control ( n = 6) and DM ( n = 6) vSMCs was quantified via qPCR and normalised to Col3a1 and Col6a1. ( C ) p21 ( n = 6) ( D ) p53, ( n = 6) ( E ) ATM ( n = 6) and ( F ) SIRT1 ( n = 6) mRNA expression from DM vSMCs was compared to controls via qPCR. ( G ) SIRT1 protein expression within DM and control vSMCs was assessed by western blot analysis and normalized to α-tubulin ( n = 6). A Mann–Whitney U test was performed. * P < 0.05, ** P < 0.01, *** P < 0.001.
    Figure Legend Snippet: Diabetic patient vSMCs exhibit DNA damage and low SIRT1 expression. ( A ) Double stranded DNA breaks were assessed via the comet assay in control ( n = 6) and diabetic (DM) ( n = 6) vSMCs. Tail moment and tail DNA percentage were calculated via CASPLab. Scale bar = 20μm. ( B ) Telomere length of control ( n = 6) and DM ( n = 6) vSMCs was quantified via qPCR and normalised to Col3a1 and Col6a1. ( C ) p21 ( n = 6) ( D ) p53, ( n = 6) ( E ) ATM ( n = 6) and ( F ) SIRT1 ( n = 6) mRNA expression from DM vSMCs was compared to controls via qPCR. ( G ) SIRT1 protein expression within DM and control vSMCs was assessed by western blot analysis and normalized to α-tubulin ( n = 6). A Mann–Whitney U test was performed. * P < 0.05, ** P < 0.01, *** P < 0.001.

    Techniques Used: Expressing, Single Cell Gel Electrophoresis, Western Blot, MANN-WHITNEY

    Related Articles

    Expressing:

    Article Title: Loss of SIRT1 in diabetes accelerates DNA damage-induced vascular calcification
    Article Snippet: Non-diabetic primary human coronary artery vSMCs were purchased from Caltag, UK.

    Single Cell Gel Electrophoresis:

    Article Title: Loss of SIRT1 in diabetes accelerates DNA damage-induced vascular calcification
    Article Snippet: Non-diabetic primary human coronary artery vSMCs were purchased from Caltag, UK.

    Western Blot:

    Article Title: Loss of SIRT1 in diabetes accelerates DNA damage-induced vascular calcification
    Article Snippet: Non-diabetic primary human coronary artery vSMCs were purchased from Caltag, UK.

    MANN-WHITNEY:

    Article Title: Loss of SIRT1 in diabetes accelerates DNA damage-induced vascular calcification
    Article Snippet: Non-diabetic primary human coronary artery vSMCs were purchased from Caltag, UK.



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    non-diabetic primary human coronary artery vsmcs  (Thermo Fisher)
    90
    Thermo Fisher non-diabetic primary human coronary artery vsmcs
    <t>Diabetic</t> patient <t>vSMCs</t> exhibit DNA damage and low SIRT1 expression. ( A ) Double stranded DNA breaks were assessed via the comet assay in control ( n = 6) and diabetic (DM) ( n = 6) vSMCs. Tail moment and tail DNA percentage were calculated via CASPLab. Scale bar = 20μm. ( B ) Telomere length of control ( n = 6) and DM ( n = 6) vSMCs was quantified via qPCR and normalised to Col3a1 and Col6a1. ( C ) p21 ( n = 6) ( D ) p53, ( n = 6) ( E ) ATM ( n = 6) and ( F ) SIRT1 ( n = 6) mRNA expression from DM vSMCs was compared to controls via qPCR. ( G ) SIRT1 protein expression within DM and control vSMCs was assessed by western blot analysis and normalized to α-tubulin ( n = 6). A Mann–Whitney U test was performed. * P < 0.05, ** P < 0.01, *** P < 0.001.
    Non Diabetic Primary Human Coronary Artery Vsmcs, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/non-diabetic+primary+human+coronary+artery+vsmcs/pmc07898956-36-0-9
    Average 90 stars, based on 1 article reviews
    non-diabetic primary human coronary artery vsmcs - by Bioz Stars, 2026-10
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Diabetic patient vSMCs exhibit DNA damage and low SIRT1 expression. ( A ) Double stranded DNA breaks were assessed via the comet assay in control ( n = 6) and diabetic (DM) ( n = 6) vSMCs. Tail moment and tail DNA percentage were calculated via CASPLab. Scale bar = 20μm. ( B ) Telomere length of control ( n = 6) and DM ( n = 6) vSMCs was quantified via qPCR and normalised to Col3a1 and Col6a1. ( C ) p21 ( n = 6) ( D ) p53, ( n = 6) ( E ) ATM ( n = 6) and ( F ) SIRT1 ( n = 6) mRNA expression from DM vSMCs was compared to controls via qPCR. ( G ) SIRT1 protein expression within DM and control vSMCs was assessed by western blot analysis and normalized to α-tubulin ( n = 6). A Mann–Whitney U test was performed. * P < 0.05, ** P < 0.01, *** P < 0.001.

    Journal: Cardiovascular Research

    Article Title: Loss of SIRT1 in diabetes accelerates DNA damage-induced vascular calcification

    doi: 10.1093/cvr/cvaa134

    Figure Lengend Snippet: Diabetic patient vSMCs exhibit DNA damage and low SIRT1 expression. ( A ) Double stranded DNA breaks were assessed via the comet assay in control ( n = 6) and diabetic (DM) ( n = 6) vSMCs. Tail moment and tail DNA percentage were calculated via CASPLab. Scale bar = 20μm. ( B ) Telomere length of control ( n = 6) and DM ( n = 6) vSMCs was quantified via qPCR and normalised to Col3a1 and Col6a1. ( C ) p21 ( n = 6) ( D ) p53, ( n = 6) ( E ) ATM ( n = 6) and ( F ) SIRT1 ( n = 6) mRNA expression from DM vSMCs was compared to controls via qPCR. ( G ) SIRT1 protein expression within DM and control vSMCs was assessed by western blot analysis and normalized to α-tubulin ( n = 6). A Mann–Whitney U test was performed. * P < 0.05, ** P < 0.01, *** P < 0.001.

    Article Snippet: Non-diabetic primary human coronary artery vSMCs were purchased from Caltag, UK.

    Techniques: Expressing, Single Cell Gel Electrophoresis, Western Blot, MANN-WHITNEY